GLP1 Protocol
Journey Guide

Week 8: Final Week at 0.5mg

This is the last full week on the 0.5mg dose before the standard step up to 1.0mg. Use it to take stock — how your body has handled the dose, which side effects faded, and which questions you want to bring to your next check-in.

Soft gradient composition representing a turning point

The Wegovy dosing schedule has you on 0.5mg for weeks 5 through 8, then 1.0mg for weeks 9 through 12. Week 8 is the final injection at this dose for most people, and it usually feels like the easiest one yet. Side effects that surfaced when you first titrated up have generally settled, appetite suppression is steady, and the weekly weight trend is reasonably consistent.

This is the moment to think about your titration decision, not after the next dose lands. Standard guidance is to step up every four weeks, but many prescribers will hold at 0.5mg longer if you are still working through nausea, reflux, or fatigue. Neither path is wrong — they just need to match your tolerance.

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Appetite Suppression

0.5mg gives most people consistent suppression. If yours has plateaued and you still have far to go, that is part of why the dose increases.

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Expected Weekly Range
1.0 - 2.0lbs

Weekly loss often holds steady at 0.5mg. Cumulative loss by end of week 8 is commonly in the 4 to 5 percent body weight range.

Week 8 Timeline

The Week 8 Timeline

vaccines

Day 50 (Injection 8)

Last 0.5mg Dose

If you are on schedule, this is your last 0.5mg injection. The familiar post-injection pattern still applies — slightly reduced appetite peak on days 2 and 3.

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Days 52-54

Take Stock

Look back at your weight and symptom log from weeks 5 through 8. Which days were hardest? Which foods did and didn't sit well? These notes guide the 1.0mg conversation.

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Day 56

Decision Point

Confirm the plan for week 9. If your prescriber agrees with the step up, your next pen will be 1.0mg. If not, you stay another cycle at 0.5mg — also normal.

Navigating Symptoms

check_circleMostly Quiet GI
infoMild Constipation
restaurantLower Food Interest

Constipation is one of the more common late-titration effects. Fiber, water, and gentle movement usually keep it manageable before the next dose step.

A practical pre-titration checklist: are you eating enough protein (a slow appetite still needs fuel), drinking enough water, and getting electrolytes if your intake has dropped? People who go into the 1.0mg week well-hydrated and well-fed tend to have an easier first few days at the higher dose.

What Users Report

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I asked my doctor about staying at 0.5mg an extra month and she was supportive. I had hit a comfortable rhythm and didn't want to risk a setback before a work trip.

— Elena R.

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Week 8 was uneventful, which felt like progress. I prepped meals for the 1.0mg week ahead — soft, protein-forward, easy on the stomach.

— Jordan A.

Looking ahead

Week 9 brings the first dose of 1.0mg. Some people sail through it; others see a brief return of week-1-style nausea. Read Week 9 on Semaglutide: Stepping Up to 1.0mg for what to plan for and how to soften the transition.