GLP1 Protocol
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All GLP-1 Journey Guides

235 hand-edited guides organized by topic, category, and medication. New guides go live every day.

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play_arrowStarting out (Weeks 1-4) · 8 guides

The first month — first injection, early appetite changes, initial side effects.

Semaglutide

Week 1 on Semaglutide: What to Expect After Your First Injection

Your first week on semaglutide at 0.25mg — what the starter dose does, common day-by-day sensations, and how to set yourself up for a steady start.

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Tirzepatide

Week 1 on Tirzepatide: Starting at 2.5mg

What to expect during your first week on tirzepatide 2.5mg — the starter dose, early appetite changes, and how to settle in.

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Semaglutide

Week 2 on Semaglutide: The Adjustment Phase

Week 2 of semaglutide at 0.25mg — the medication starts to build up, side effects can peak, and food noise begins to fade for many people.

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Tirzepatide

Week 2 on Tirzepatide: Settling Into the Starter Dose

Week 2 of tirzepatide at 2.5mg — what changes after your second injection, common side effects, and how to read your body's signals.

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Semaglutide

Week 3 on Semaglutide: Finding Your Rhythm

What to expect in week 3 of semaglutide treatment — appetite suppression stabilizes, side effects ease, and the journey hits its rhythm.

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Tirzepatide

Week 3 on Tirzepatide: Finding Your Rhythm at 2.5mg

Week 3 on tirzepatide 2.5mg — appetite suppression strengthens, side effects ease, and the starter phase finds its rhythm.

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Semaglutide

Week 4 on Semaglutide: Closing Out the Starter Dose

Week 4 of semaglutide closes out the 0.25mg starter dose — what to expect, how to tell if you are ready to titrate up, and how to prepare for 0.5mg.

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Tirzepatide

Week 4 on Tirzepatide: Last Week Before the First Step Up

Week 4 on tirzepatide — the final week at 2.5mg before titrating to 5mg. What to expect and how to prepare for the dose increase.

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