GLP1 Protocol
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All GLP-1 Journey Guides

235 hand-edited guides organized by topic, category, and medication. New guides go live every day.

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scheduleTherapeutic phase (Weeks 13-24) · 12 guides

Settling into higher doses through month six. Habits consolidate.

Semaglutide

Week 13 on Semaglutide: Titrating Toward 1.7mg

Week 13 brings the jump from 1.0mg to 1.7mg semaglutide. Side effects can flare briefly. Here is what to expect and how to handle the new dose.

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Semaglutide

Week 14 on Semaglutide: Settling at 1.7mg

Week 14 is the second injection at 1.7mg. The titration shock typically fades and the new dose becomes the new baseline. Here is what to expect.

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Semaglutide

Week 15 on Semaglutide: Mid-Titration Steady

Week 15 is the midpoint of the 1.7mg block. Side effects are usually quiet, weight loss is steady, and the focus shifts to habits over heroics.

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Semaglutide

Week 16 on Semaglutide: Closing Out 1.7mg

Week 16 is the last week at 1.7mg before the final titration to 2.4mg. Here is how to review progress and prepare for the target dose.

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Semaglutide

Week 17 on Semaglutide: Stepping Up to 2.4mg

Week 17 brings the final titration to 2.4mg, the target Wegovy dose. Side effects can briefly return. Here is what to expect at the top of the schedule.

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Semaglutide

Week 18 on Semaglutide: First Week on the Target Dose

Week 18 is the second injection at 2.4mg. The titration shock fades, the target dose becomes the new baseline, and maintenance work begins.

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Semaglutide

Week 19 on Semaglutide: Settling Into 2.4mg

Week 19 is the third week at 2.4mg. The target dose feels routine, side effects are usually quiet, and the focus shifts to sustainable habits.

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Semaglutide

Week 20 on Semaglutide: Steady at Target

Week 20 closes the first full month at 2.4mg semaglutide. The dose is settled, habits are consolidating, and the long maintenance phase begins.

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Semaglutide

Week 21 on Semaglutide: Five Months In

Week 21 marks five months on semaglutide. The dose is settled, habits are deepening, and the long maintenance phase reveals its rhythm.

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Semaglutide

Week 22 on Semaglutide: Building Habits at Target Dose

Week 22 is deep in the 2.4mg maintenance phase. Habits are doing more of the work than novelty. Here is what to focus on at this stage.

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Semaglutide

Week 23 on Semaglutide: Approaching the Half-Year Mark

Week 23 is the last week before the six-month milestone on semaglutide. A natural time to prepare data and questions for the half-year review.

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Semaglutide

Week 24 on Semaglutide: The Six-Month Milestone

Week 24 marks six months on semaglutide. STEP trial data shows ~10% mean body-weight loss at this point. Here is how to review and plan ahead.

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