All GLP-1 Journey Guides
235 hand-edited guides organized by topic, category, and medication. New guides go live every day.
scheduleTherapeutic phase (Weeks 13-24) · 12 guides
Settling into higher doses through month six. Habits consolidate.
Week 13 on Tirzepatide: Stepping Up to 10mg
Week 13 on tirzepatide is the first injection at 10mg. Expect a brief return of GI side effects, a deeper appetite quiet, and a higher weekly loss range.
Read guidearrow_forwardWeek 14 on Tirzepatide: Settling at 10mg
Week 14 on tirzepatide is the first full settled week at 10mg. Side effects ease, appetite suppression stabilizes, and the loss trend resumes.
Read guidearrow_forwardWeek 15 on Tirzepatide: Mid-10mg Plateau Watch
Week 15 on tirzepatide is the mid-cycle mark at 10mg. The honeymoon ends for some, the trend continues for others — here is how to read the scale this week.
Read guidearrow_forwardWeek 16 on Tirzepatide: Closing Out 10mg
Week 16 on tirzepatide is the final dose at 10mg before the next titration window. Time to review the four-week trend and prepare the 12.5mg conversation.
Read guidearrow_forwardWeek 17 on Tirzepatide: Stepping Up to 12.5mg
Week 17 on tirzepatide is the first injection at 12.5mg. Side effects can return briefly, appetite suppression deepens, and the loss curve often reaccelerates.
Read guidearrow_forwardWeek 18 on Tirzepatide: Settling Into 12.5mg
Week 18 on tirzepatide is the first settled week at 12.5mg. The titration bump fades, appetite stays near-silent, and the trend continues at a sustainable pace.
Read guidearrow_forwardWeek 19 on Tirzepatide: Mid-12.5mg
Week 19 on tirzepatide is the mid-cycle mark at 12.5mg. The dose is at full steady state and the loss trend, with or without a flat week, is the focus.
Read guidearrow_forwardWeek 20 on Tirzepatide: Closing Out 12.5mg
Week 20 on tirzepatide is the final dose at 12.5mg before the 15mg window opens. Time to weigh maximum-dose benefits against staying where you are.
Read guidearrow_forwardWeek 21 on Tirzepatide: Stepping Up to 15mg
Week 21 on tirzepatide is the first injection at the 15mg maximum dose. Side effects can return, appetite goes near-silent, and the loss curve gets its final boost.
Read guidearrow_forwardWeek 22 on Tirzepatide: First Full Week at 15mg
Week 22 on tirzepatide is the first settled week at the maximum 15mg dose. Titration noise is gone, appetite is near-total, and the trend continues at a sustainable slope.
Read guidearrow_forwardWeek 23 on Tirzepatide: Approaching the Half-Year Mark
Week 23 on tirzepatide is the third dose at 15mg and the last week before the six-month milestone. Time to prepare the data and read the half-year picture.
Read guidearrow_forwardWeek 24 on Tirzepatide: The Six-Month Milestone
Week 24 on tirzepatide marks six months. SURMOUNT-1 puts cumulative loss near 20% on 15mg at this point. Time to review the half-year and plan ahead.
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