GLP1 Protocol
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All GLP-1 Journey Guides

115 hand-edited guides organized by topic, category, and medication. New guides go live every day.

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trending_upTitration phase (Weeks 5-12) · 8 guides

Stepping up doses through the first three months toward your therapeutic dose.

Semaglutide

Week 10 on Semaglutide: Settling into 1.0mg

Week 10 of semaglutide is when 1.0mg starts to feel normal. Side effects ease, appetite suppression holds, and a clearer weight trend often emerges.

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Tirzepatide

Week 10 on Tirzepatide: Settling into 7.5mg

Week 10 is your second week at 7.5mg tirzepatide. Side effects typically ease and appetite suppression deepens. Here is what to track.

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Semaglutide

Week 11 on Semaglutide: Hitting Your Rhythm

Week 11 is the steady middle of the 1.0mg phase. Appetite suppression is reliable, side effects are usually minimal, and non-scale wins start adding up.

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Tirzepatide

Week 11 on Tirzepatide: Adjusting to the Therapeutic Dose

Week 11 on tirzepatide: 7.5mg is now your steady-state dose. Here is how appetite, energy, weight, and side effects typically behave at this milestone.

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Semaglutide

Week 12 on Semaglutide: The First Big Milestone

Week 12 marks three months on semaglutide. Average cumulative loss approaches 6% body weight per STEP trial data. Here's how to review and plan ahead.

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Tirzepatide

Week 12 on Tirzepatide: The First Big Milestone

Week 12 on tirzepatide marks three months and your first major checkpoint. Review weight, side effects, lab work, and the decision about the next dose.

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Semaglutide

Week 8 on Semaglutide: Final Week at 0.5mg

Week 8 is your last week at 0.5mg before titration to 1.0mg. Here's how to prepare, what side effects to expect, and how to talk to your prescriber.

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Tirzepatide

Week 8 on Tirzepatide: Last Week at 5mg

Week 8 closes the 5mg phase of tirzepatide. Review side effects, weight trends, and how to prepare for the standard titration to 7.5mg.

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