All GLP-1 Journey Guides
115 hand-edited guides organized by topic, category, and medication. New guides go live every day.
Journey · 12 guides
Week-by-week guides for both medications
play_arrowStarting out (Weeks 1-4) (3)
The first month — first injection, early appetite changes, initial side effects.
Week 1 on Tirzepatide: Starting at 2.5mg
What to expect during your first week on tirzepatide 2.5mg — the starter dose, early appetite changes, and how to settle in.
Read guidearrow_forwardWeek 2 on Tirzepatide: Settling Into the Starter Dose
Week 2 of tirzepatide at 2.5mg — what changes after your second injection, common side effects, and how to read your body's signals.
Read guidearrow_forwardWeek 4 on Tirzepatide: Last Week Before the First Step Up
Week 4 on tirzepatide — the final week at 2.5mg before titrating to 5mg. What to expect and how to prepare for the dose increase.
Read guidearrow_forwardtrending_upTitration phase (Weeks 5-12) (4)
Stepping up doses through the first three months toward your therapeutic dose.
Week 10 on Tirzepatide: Settling into 7.5mg
Week 10 is your second week at 7.5mg tirzepatide. Side effects typically ease and appetite suppression deepens. Here is what to track.
Read guidearrow_forwardWeek 11 on Tirzepatide: Adjusting to the Therapeutic Dose
Week 11 on tirzepatide: 7.5mg is now your steady-state dose. Here is how appetite, energy, weight, and side effects typically behave at this milestone.
Read guidearrow_forwardWeek 12 on Tirzepatide: The First Big Milestone
Week 12 on tirzepatide marks three months and your first major checkpoint. Review weight, side effects, lab work, and the decision about the next dose.
Read guidearrow_forwardWeek 8 on Tirzepatide: Last Week at 5mg
Week 8 closes the 5mg phase of tirzepatide. Review side effects, weight trends, and how to prepare for the standard titration to 7.5mg.
Read guidearrow_forwardscheduleTherapeutic phase (Weeks 13-24) (1)
Settling into higher doses through month six. Habits consolidate.
eventMonth markers (Month 3 - 12) (4)
Three-month checkpoints from month three through year one.
Month 12 on Tirzepatide: One Year of Treatment Reviewed
One year on tirzepatide. SURMOUNT-1 reports up to ~20.9% mean weight loss at 72 weeks on 15mg. Review labs, dose, lean mass, and the long-term plan.
Read guidearrow_forwardMonth 3 on Tirzepatide: The First Real Milestone
Month 3 on tirzepatide is the standard checkpoint. SURMOUNT-1 shows ~10% cumulative loss by 12 weeks on the higher dose. Time to review and plan.
Read guidearrow_forwardMonth 6 on Tirzepatide: Halfway Through the First Year
Month 6 on tirzepatide marks halfway. SURMOUNT-1 shows ~15% cumulative loss on the higher dose. Dose at 10mg, side effects routine, plateaus possible.
Read guidearrow_forwardMonth 9 on Tirzepatide: Where the Curve Levels Out
Month 9 on tirzepatide is where the steep loss curve begins to flatten. SURMOUNT-1 shows ~18% cumulative loss on the higher dose at this stage.
Read guidearrow_forward