All GLP-1 Journey Guides
235 hand-edited guides organized by topic, category, and medication. New guides go live every day.
Journey · 28 guides
Week-by-week guides for both medications
play_arrowStarting out (Weeks 1-4) (4)
The first month — first injection, early appetite changes, initial side effects.
Week 1 on Tirzepatide: Starting at 2.5mg
What to expect during your first week on tirzepatide 2.5mg — the starter dose, early appetite changes, and how to settle in.
Read guidearrow_forwardWeek 2 on Tirzepatide: Settling Into the Starter Dose
Week 2 of tirzepatide at 2.5mg — what changes after your second injection, common side effects, and how to read your body's signals.
Read guidearrow_forwardWeek 3 on Tirzepatide: Finding Your Rhythm at 2.5mg
Week 3 on tirzepatide 2.5mg — appetite suppression strengthens, side effects ease, and the starter phase finds its rhythm.
Read guidearrow_forwardWeek 4 on Tirzepatide: Last Week Before the First Step Up
Week 4 on tirzepatide — the final week at 2.5mg before titrating to 5mg. What to expect and how to prepare for the dose increase.
Read guidearrow_forwardtrending_upTitration phase (Weeks 5-12) (8)
Stepping up doses through the first three months toward your therapeutic dose.
Week 10 on Tirzepatide: Settling into 7.5mg
Week 10 is your second week at 7.5mg tirzepatide. Side effects typically ease and appetite suppression deepens. Here is what to track.
Read guidearrow_forwardWeek 11 on Tirzepatide: Adjusting to the Therapeutic Dose
Week 11 on tirzepatide: 7.5mg is now your steady-state dose. Here is how appetite, energy, weight, and side effects typically behave at this milestone.
Read guidearrow_forwardWeek 12 on Tirzepatide: The First Big Milestone
Week 12 on tirzepatide marks three months and your first major checkpoint. Review weight, side effects, lab work, and the decision about the next dose.
Read guidearrow_forwardWeek 5 on Tirzepatide: Titrating Up to 5mg
Week 5 on tirzepatide — your first dose increase to 5mg. What changes, what side effects to expect, and how to ride out the bump.
Read guidearrow_forwardWeek 6 on Tirzepatide: Adjusting to 5mg
Week 6 on tirzepatide 5mg — the side-effect rebound fades and the new appetite baseline settles in. What to track and how to read your body.
Read guidearrow_forwardWeek 7 on Tirzepatide: Halfway Through 5mg
Week 7 marks the midpoint of your 5mg tirzepatide phase. Here is what to expect: steadier appetite control, weight loss patterns, and side effect trends.
Read guidearrow_forwardWeek 8 on Tirzepatide: Last Week at 5mg
Week 8 closes the 5mg phase of tirzepatide. Review side effects, weight trends, and how to prepare for the standard titration to 7.5mg.
Read guidearrow_forwardWeek 9 on Tirzepatide: Titrating to 7.5mg
Your first week on 7.5mg tirzepatide. What appetite changes, side effects, and weight trends to expect during this important step-up.
Read guidearrow_forwardscheduleTherapeutic phase (Weeks 13-24) (12)
Settling into higher doses through month six. Habits consolidate.
Week 13 on Tirzepatide: Stepping Up to 10mg
Week 13 on tirzepatide is the first injection at 10mg. Expect a brief return of GI side effects, a deeper appetite quiet, and a higher weekly loss range.
Read guidearrow_forwardWeek 14 on Tirzepatide: Settling at 10mg
Week 14 on tirzepatide is the first full settled week at 10mg. Side effects ease, appetite suppression stabilizes, and the loss trend resumes.
Read guidearrow_forwardWeek 15 on Tirzepatide: Mid-10mg Plateau Watch
Week 15 on tirzepatide is the mid-cycle mark at 10mg. The honeymoon ends for some, the trend continues for others — here is how to read the scale this week.
Read guidearrow_forwardWeek 16 on Tirzepatide: Closing Out 10mg
Week 16 on tirzepatide is the final dose at 10mg before the next titration window. Time to review the four-week trend and prepare the 12.5mg conversation.
Read guidearrow_forwardWeek 17 on Tirzepatide: Stepping Up to 12.5mg
Week 17 on tirzepatide is the first injection at 12.5mg. Side effects can return briefly, appetite suppression deepens, and the loss curve often reaccelerates.
Read guidearrow_forwardWeek 18 on Tirzepatide: Settling Into 12.5mg
Week 18 on tirzepatide is the first settled week at 12.5mg. The titration bump fades, appetite stays near-silent, and the trend continues at a sustainable pace.
Read guidearrow_forwardWeek 19 on Tirzepatide: Mid-12.5mg
Week 19 on tirzepatide is the mid-cycle mark at 12.5mg. The dose is at full steady state and the loss trend, with or without a flat week, is the focus.
Read guidearrow_forwardWeek 20 on Tirzepatide: Closing Out 12.5mg
Week 20 on tirzepatide is the final dose at 12.5mg before the 15mg window opens. Time to weigh maximum-dose benefits against staying where you are.
Read guidearrow_forwardWeek 21 on Tirzepatide: Stepping Up to 15mg
Week 21 on tirzepatide is the first injection at the 15mg maximum dose. Side effects can return, appetite goes near-silent, and the loss curve gets its final boost.
Read guidearrow_forwardWeek 22 on Tirzepatide: First Full Week at 15mg
Week 22 on tirzepatide is the first settled week at the maximum 15mg dose. Titration noise is gone, appetite is near-total, and the trend continues at a sustainable slope.
Read guidearrow_forwardWeek 23 on Tirzepatide: Approaching the Half-Year Mark
Week 23 on tirzepatide is the third dose at 15mg and the last week before the six-month milestone. Time to prepare the data and read the half-year picture.
Read guidearrow_forwardWeek 24 on Tirzepatide: The Six-Month Milestone
Week 24 on tirzepatide marks six months. SURMOUNT-1 puts cumulative loss near 20% on 15mg at this point. Time to review the half-year and plan ahead.
Read guidearrow_forwardeventMonth markers (Month 3 - 12) (4)
Three-month checkpoints from month three through year one.
Month 12 on Tirzepatide: One Year of Treatment Reviewed
One year on tirzepatide. SURMOUNT-1 reports up to ~20.9% mean weight loss at 72 weeks on 15mg. Review labs, dose, lean mass, and the long-term plan.
Read guidearrow_forwardMonth 3 on Tirzepatide: The First Real Milestone
Month 3 on tirzepatide is the standard checkpoint. SURMOUNT-1 shows ~10% cumulative loss by 12 weeks on the higher dose. Time to review and plan.
Read guidearrow_forwardMonth 6 on Tirzepatide: Halfway Through the First Year
Month 6 on tirzepatide marks halfway. SURMOUNT-1 shows ~15% cumulative loss on the higher dose. Dose at 10mg, side effects routine, plateaus possible.
Read guidearrow_forwardMonth 9 on Tirzepatide: Where the Curve Levels Out
Month 9 on tirzepatide is where the steep loss curve begins to flatten. SURMOUNT-1 shows ~18% cumulative loss on the higher dose at this stage.
Read guidearrow_forward